His agent Matt Frost confirmed the news in a statement, while expressing his gratitude towards Patrice's fans and friends who expressed support as he battled for his life following the stroke on Oct. 19. He states that O'Neal's mother, Gloria, was right by his side until his very last breath. Aside from his later issues with the stroke, Patrice was also 300 pounds and struggled with diabetes for the majority of his adult life.
The hosts of Sirius XM radio show "Opie and Anthony" (and friends of O'Neal) were the first to broadcast the devastating news. Gregg (Opie) tweeted:"Yes, it's true that our pal Patrice O'Neal has passed away. The funniest and best thinker I've ever known PERIOD #devastated." Healso provided a link to a video of his late friend laughing on the radio show and added: "Patrice O'Neal Greatest Laugh EVER."
Patrice O'Neal's last television appearance was during Comedy Central Roast of Charlie Sheen. "The entertainment world, as well as the world at large, lost a brilliant man...I only knew him for the few days leading up to the Roast. Yet, I will forever be inspired by his nobility, his grace and his epic talent," Charlie Sheen said in a statement.
O'Neal is survived by his wife, Vondecarlo, a step-daughter, Aymilyon, and his sister, Ziner. We express our deepest condolences to his family and loved ones. Rest in peace.